Common gene variants explain 42% of antidepressant response:

Mar. 28, 2013 — Antidepressants are commonly prescribed for the treatment
of depression, but many individuals do not experience symptom relief from
treatment. The National Institute of Mental Health’s STAR*D study, the
largest and longest study ever conducted to evaluate depression treatment,
found that only approximately one-third of patients responded within their
initial medication trial and approximately one-third of patients did not
have an adequate clinical response after being treated with several
different medications. Thus, identifying predictors of antidepressant
response could help to guide the treatment of this disorder.

A new study published in *Biological Psychiatry *now shares progress in
identifying genomic predictors of antidepressant response.

*Common gene variants explain 42% of antidepressant response*